Capability Title | Fully equipped organic synthesis capabilities |
Laboratories | Los Alamos National Laboratory (LANL), Pacific Northwest National Laboratory (PNNL), Sandia National Laboratories (SNL) |
Capability experts | Joey Carlson (SNL), Lelia Cosimbescu (PNNL), Andrew Sutton (LANL) |
Description |
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Limitations | Batch reactions can scale up to 1-3L flask or 10L glass reactor. It may be more efficient to run several 1-3L scale in parallel where the process is well defined than to use 10L reactor. |
Unique aspects | Though not unique, the ability to go from concept to screening to validation and then moderate scale-up is unusual. |
Availability | At all times, with appropriate prioritization. |
Citations/references |
J.P. Page, J.W. Robinson, K.O. Albrecht, L. Cosimbescu. 2018. “Synthesis of a biofuel target through conventional organic chemistry.” Tetrahedron Letters 59:14 1421-1423. http:/doi.org/10.1016/j.tetlet.2018.02.073. E. Polikarpov, K. O. Albrecht, J. P. Page, D. Malhotra, P. K. Koech, L. Cosimbescu, and D. J. Gaspar. 2019. “Critical fuel property evaluation for potential gasoline and diesel biofuel blendstocks with low sample volume availability.” Fuel 238 26-33. https://doi.org/10.1016/j.fuel.2018.09.129. |